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MyopiaTracker Clinical Team
Reviewed by Dr. Balamurali Vasudevan, BSOptom, PhD, FAAO, MBA · Last updated: April 2026

Best Myopia Treatments Ranked by What Actually Works
2026 Evidence-Based Guide

Short answer: The treatments with the strongest evidence are Stellest® spectacle lenses (67% AL reduction), MiSight® contact lenses (55%), orthokeratology (50%), and atropine drops (30–58% depending on concentration). The best option depends on your child's age, progression rate, and lifestyle.

For clinicians: See the detailed RCT comparison with AL endpoints, study populations, and study duration. MiSight vs Stellest → · Atropine outcomes →
67%
Best single-modality efficacy in full-time wearers: Stellest® HAL lenses (Bao et al. 2022, 2-year RCT; ITT ~51%)
~75%
Maximum achievable efficacy: combination therapy (modeled multiplicative estimate, capped)
Now
When to start, per IMI 2025 — at diagnosis, not when progression becomes "fast enough"

All treatment options ranked by efficacy

TreatmentAL reduction vs untreatedKey trialMin age / notes
Combination therapy †~68% (modeled)Multiplicative modelAny age; stacks two modalities
Stellest® HAL lenses67% (≥12hr/day wear); ~51% ITTBao et al. 2022School age; worn ≥12hr/day
Atropine 0.05%~58% at 3 yearsLAMP (Yam et al. 2019)Any age; compounded drops
MiSight® 1 day~55% at 3 yearsChamberlain et al. 2019FDA-approved age 8–12
MiyoSmart® DIMS~52% at 2 yearsLam et al. 2020School age; spectacle lenses
Orthokeratology~50% (meta-analysis)Multiple RCTsFrom ~age 7; overnight lenses
Atropine 0.025%~45% at 2 yearsLAMP (Yam et al. 2019)Any age; compounded drops
Atropine 0.01%~30% at 2 yearsATOM2 (Chia et al. 2012)Any age; fewest side effects
Outdoor time (≥2hr/day)~18% onset reductionWu et al. 2018All ages; less effect once established

† Combination therapy efficacy is a modeled composite (multiplicative, capped at 75%). No single RCT directly validates a specific combination at these figures. Efficacy values represent change in axial elongation vs untreated control at ~2-year endpoints. Individual outcomes vary. Treatment availability and regulatory approval vary by country.

Choosing the right treatment

Under age 8 — or contact lens not suitable

Stellest® or MiyoSmart® spectacle lenses, or atropine 0.01–0.025% drops. No contact fitting required. Atropine can be added to spectacle lenses for additive effect.

Age 8–12, moderate progression

MiSight® (FDA-approved) or Stellest® are the leading options. MiSight requires daily contact lens handling; Stellest requires wearing the lenses ≥12 hours per day for full effect.

Fast progression at any age

Combination therapy — typically orthokeratology or MiSight® plus atropine. Produces the highest achievable efficacy. Consider if single-modality treatment is insufficient.

Prefers no daytime lenses

Orthokeratology — worn only overnight, providing glasses-free daytime vision. Requires nightly lens care and fitting by an experienced OD.

What about LASIK?

LASIK corrects vision but does not slow progression or reduce axial length. It is not a myopia management treatment and is generally recommended only after myopia has stabilised (typically not before age 21). See Is LASIK safe for myopia?

When to start

The IMI 2025 consensus: at diagnosis, not when progression becomes "fast enough." Every year of fast progression without intervention is permanently added to lifetime axial length and cannot be recovered.

See projected outcomes for your child's data

Enter age and axial length measurements. Get all 9 treatment modalities projected to age 18 — side by side — based on your child's actual growth rate. Or see all treatments compared: myopia treatment comparison →

Compare all treatments →

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Sources: Bao J et al. JAMA Ophthalmol. 2022;140(1):16–24 · Chamberlain P et al. Optom Vis Sci. 2019;96(8):556–567 · Yam JC et al. Ophthalmology. 2019;126(1):113–124 · Chia A et al. Ophthalmology. 2012;119(2):347–354 · Lam CSY et al. Lancet. 2020;396(10240):70–77 · IMI 2025 Digest

This page is for educational purposes and does not constitute medical advice. MyopiaTracker is a decision-support tool — not a diagnostic device. MiSight® is a registered trademark of The Cooper Companies. Stellest® is a registered trademark of Essilor International. MiyoSmart® is a registered trademark of Hoya Corporation. Treatment availability and regulatory approval vary by country. Consult a qualified optometrist or ophthalmologist for personalised advice.

About the reviewer: Dr. Balamurali Vasudevan (BSOptom, PhD, FAAO, MBA) is an Associate Professor and Vision Science Lead at Midwestern University, AZ, with 54+ peer-reviewed publications and 20+ years in clinical vision science and myopia research. Former Senior Clinical Vision Scientist at Johnson & Johnson Vision Care. All clinical content on MyopiaTracker is reviewed for accuracy against primary literature before publication.
Related Resources
MiSight® vs Stellest® — deep dive comparison → Atropine 0.01% vs 0.025% vs 0.05% → Orthokeratology — overnight AL control → When should treatment start? → Compare all 9 treatments for your patient →